Your health, our mission

Research

Research

CHAPS evolved from the Orange Farm research programme and team that, in the 5 years prior to 2010, had researched and published extensively around the topic of voluntary medical male circumcision. The research and the publications of the Orange Farm team, most notably the randomised controlled trial which demonstrated the 60% protective benefit of medical male circumcision, contributed to the World Health Organization (WHO) recommendations in 2007.

Today, CHAPS is most recognised for its biomedical research and community-based research in the scale-up of voluntary medical male circumcision (VMMC) for HIV prevention in South Africa and the region. However, with both programmatic and research expertise, we are able to offer community-based research and feasibility studies in a number of areas.

Research, publications and conference presentations

Ongoing Research

2015 
Developing safe, cost-effective and sustainable service delivery models for early infant male circumcision (EIMC) in South Africa.

Research Funded by: UNICEF

Building A Clinical Profile for A New Voluntary Medical Male Circumcision Surgical Aid Device: A Randomised Control Trial for Building the Clinical Profile for a New VMMC Device Application for Pre-qualification Dossier

Research Funded by: SAFIKA House

Evaluation of the Acceptability and Safety of the PrePex Device  Adult Male Circumcision in South Africa: A Pilot Study in Three Clinical Sites 

Research Funded by: USAID through ANOVA

Reports 

2015
Dean, G.N., Frade, S., Mabena, N., Taljaard, D. & Rech, D. (2015). A Case Series Non-Comparative Study in South Africa: CircumQ

2013
Bertrand JT, Rech D, Dickens O, Frade S, Loolpapit M, Machaku MD, Mavhu W, Onyango M, Spyrelis A, Perry L, Farrell-Ross M. (2013). Systematic Monitoring of the Male Circumcision Scale-up in Eastern and Southern Africa (SYMMACS): Final Report of results from Kenya, South Africa, Tanzania, and Zimbabwe. Baltimore: USAID │Project Search: Research to Prevention. 

Research supported by: Johns Hopkins Bloomberg School of Public Health Center for Communication Programs (CCP) and Johns Hopkins Center for Global Health.

Research Funded by: The USAID|Project SEARCH and PEPFAR

Spyrelis A, Frade S, Rech D, & Taljaard D. (2013). Acceptability of Early Infant Male Circumcision in two South African communities. Johannesburg: CHAPS.
Johnson T, Spyrelis A, Frade S, Rech D, & Taljaard D. (2013). Training follow-up study. Johannesburg: CHAPS.

2012
Nieuwoudt S, Frade S, Rech D, & Taljaard D. (2012). Uncovering the “dirt” on Demand Creation for Medical Male Circumcision. Johannesburg: CHAPS
Bertrand JT, Rech D, Dickens O, Frade S, Loolpapit M, Machaku MD, Mavhu W, Perry L & Farrell-Ross M. (2012). Systematic Monitoring of the Male Circumcision Scale-up in Eastern and Southern Africa (SYMMACS): Interim Report of results from Kenya, South Africa, Tanzania, and Zimbabwe. Baltimore: USAID │Project Search: Research to Prevention.

Research supported by: Johns Hopkins Bloomberg School of Public Health Center for Communication Programs (CCP) and Johns Hopkins Center for Global Health.

Research Funded by: The USAID|Project SEARCH and PEPFAR

2011
Rech D, Dickson KE, Samkange C, et al. (2011). Adverse Event Action Guide for Male Circumcision. PSI and WHO: Washington, DC.

2010
World Health Organization. (2010). Considerations for implementing Models for Optimizing the Volume and Efficiency of Male Circumcision Services. Geneva: WHO.
Center for Global Health Policy. (2010). Medical Male Circumcision as HIV Prevention, Follow the Evidence: The case for aggressive scale up. Center for Global Health Policy: Washington, DC.

2009
World Health Organization. (2009). Guidance on engaging volunteers to support the scale up of male circumcision services. Geneva: WHO.
PEPFAR. (2009). PEPFAR Male Circumcision Partner’s Meeting: Commodities and Improved Coordination of Male Circumcision for HIV Prevention. Washington, DC: PEPFAR.

Conference presentations and posters

2016
21st International AIDS Conference (AIDS 2016)
Dean, G. N., Frade, S., Rech, D., & Taljaard, D. (2016). Clinical outcomes from a pilot study examining the PrePex device for VMMC in South Africa. Poster Presentation Presented at the AIDS 2016 Conference, Durban, 18-22 July 2016 
Abdulla, S., Frade, S., Ndhlovu, R., Rech, D., &  Taljaard, D. (2016). Effectiveness of mobile clinics offering VMMC in marginalised communities as an HIV prevention intervention. Poster Presentation Presented at the AIDS 2016 Conference, Durban, 18-22 July 2016 
Haté, V., Dean, GN., Frade, S., Rech, D., Taljaard, D.,  Stegman, P., &  Kripke, K. (2016). Does introduction of PrePexTM into an existing surgical VMMC program save money? Poster Presentation Presented at the AIDS 2016 Conference, Durban, 18-22 July 2016 
Khehla-Adams, A., Rech, D., Maziya, V., & Vandelanotte, J. (2016). Increasing uptake of Circumcision Services among 15-29 old Swazi males through Private Practitioners. Poster Presentation Presented at the AIDS 2016 Conference, Durban, 18-22 July 2016 
Otchere- Darko, J., Monji, L.., Satande, L.,  Sbu, S., Capati  J., & Rech, D. (2016). The impact of clinical associates on expanding high-quality, cost-effective voluntary medical male circumcision (VMMC) services in South Africa. Poster Presentation Presented at the AIDS 2016 Conference, Durban, 18-22 July 2016

2015
14th World Conference on Public Health (WCPH), Kolkata, India
Dean, G. N.,  Frade, S., Spyrelis, A., Abdulla, S., Rech, D., & Taljaard, D. (2015). Cultural and traditional factors affecting the likelihood of parents’ uptake of early infant male circumcision (EIMC) in Soweto and Orange Farm, South Africa. Oral Session presented at the 14th World Conference on Public Health (WCPH), Kolkata, India.
Abdulla, S., Spyrelis, A., Frade, S., Meyer. T., Mhazo. M., Taljaard, D., & Billy, S. (2015). “It’s a good idea and then again it’s not”: The perceived advantages and disadvantages in scaling-up the HIV self-testing kit in Johannesburg, South Africa. Oral Session presented at the 14th World Conference on Public Health (WCPH), Kolkata, India.

2014
Conference on Retroviruses and Opportunistic Infections (CROI), Boston, USA
 

Auvert B, Lissouba P, Taljaard D, Peytavin G, Singh B & Puren A. (2014, March). Male circumcision – Association with HIV prevalence, knowledge, and attitudes among women: Findings from the ANRS 12126 study.  Poster session presented at the annual Conference on Retroviruses and Opportunistic Infections (CROI), Boston, USA.

2013
South African AIDS Conference (SAAIDS), Durban, South Africa
Frade S, Nieuwoudt S, Rech D, Spyrelis A, & Taljaard D. (2013, June). Culture and tradition as key factors in voluntary medical male circumcision (VMMC) decision-making in Gauteng, South Africa. Poster session presented at the 6th South African AIDS Conference (SAAIDS), Durban, South Africa. 
Spyrelis A, Nieuwoudt S, Frade S, Rech D, & Taljaard D. (2013, June). Peers, sexual partners and family: An exploration of ‘informal’ demand creation in voluntary medical male circumcision (VMMC) in Soweto and Orange Farm, South Africa. Poster session presented at the 6th South African AIDS Conference (SAAIDS), Durban, South Africa. 
Spyrelis A, Frade S, Rech D, Taljaard D, & Bertrand JT. (2013, June). Provider opinions on the voluntary medical male circumcision (VMMC) scale-up in South Africa. Poster session presented at the 6th South African AIDS Conference (SAAIDS), Durban, South Africa. 
S Frade, D Rech, A Spyrelis, M Machaku, W Mavhu, D Omondi , M Onyango , M Farrell-Ross, & J Bertrand. (2013, June). Seasonal patterns in voluntary medical male circumcision (VMMC) in South Africa, Kenya, Tanzania and Zimbabwe. Poster session presented at the 6th South African AIDS Conference (SAAIDS), Durban, South Africa. 
7th International AIDS Conference (IAS), Kuala Lumpur, Malaysia
Rech D, Frade S, Spyrelis A, Perry L, Toledo C, Fertziger R, Njeuhmeli E, & Bertrand JT. (2013, July).Implications of the rapid scale up and the expansion of VMMC in South Africa for quality of services.Paper presented at the 7th International AIDS Conference (IAS), Kuala Lumpur, Malaysia. 
Bertrand J, Rech D, Njeuhmeli E, Castor D, Frade S, Loolpapit M, Machaku M, Mavhu W, & Perry L. (2013, July). Determinants of VMMC Provider Burnout in Four Sub-Saharan countries. Poster session presented at the 7th International AIDS Conference (IAS), Kuala Lumpur, Malaysia.
Nieuwoudt S, Frade S, Spyrelis A, Taljaard D, & Rech D. (2013, July). Sexual pleasure, reduced STIs and peer norms: underlying motivations for seeking VMMC in Gauteng, South Africa. Poster session presented at the 7th International AIDS Conference (IAS), Kuala Lumpur, Malaysia. 
Rech D, Reed J, Frade S, Samkange CA, Thomas N, Farrell M, Castor D, Njeuhmeli E, & Bertrand J. (2013, July). Efficiencies in the performance of voluntary medical male circumcision (VMMC) procedures. Poster session presented at the 7th International AIDS Conference (IAS), Kuala Lumpur, Malaysia.

2012
XIX International AIDS Conference, Washington DC, USA
Auvert B, Taljaard D, Sitta R, Rech D, Lissouba P, Bouscaillou J, Singh B, Shabangu D, Nhlapo C, Otchere-Darko J, Mashigo T, Taljaard R, Phatedi G, Tsepe M, Chakela M, Mkhwanazi A, Ntshangase P, Peytavin G, Billy S, Puren A, & Lewis D. (2012, July). Decrease of HIV prevalence over time among the male population of Orange Farm, South Africa, following a circumcision roll-out (ANRS-12126). Poster session presented at the 19th International AIDS Conference, Washington, DC, USA.
Taljaard D, Rech D, Frade S, McIntyre J, Struthers H, & Plank R. (2012, July). Feasibility of circumcising male infants in Soweto and Orange Farm, South Africa:  Why would parents circumcise their infants?Poster session presented at the 19th International AIDS Conference, Washington, DC, USA.

2009
5th International AIDS Conference on HIV Pathogenesis, Treatment & Prevention
Auvert B, Lissouba P, Cutler E, Zarca K, Puren A, & Taljaard D. (2009, July). Is genital human papillomavirus infection associated with HIV incidence? Paper presented at the 5th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, Cape Town, South Africa.

For more information on our research-related services, email Genevieve Dean on gen@chaps.org.za

CONTACT

Address: 25st John’s Road, Houghton Estate, 2198
Tel: 011 484 8068
Fax: +27 86 556 4331
Email: info@chaps.org.za

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